p.Pro36 Leu39del variant of TMEM127 (Transmembrane protein 127)

Name: TMEM127 p.Pro36 Leu39del variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-21
License: https://catvariant.com/terms-of-use

p.Pro36 Leu39del in TMEM127 (Transmembrane protein 127) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.

p.Pro36 Leu39del variant details

gnomAD 2-96265264-ACAGGG
Inframe Deletion
Variant Prioritization Score for Impact Estimate 0.601
CADD 22.50
Most common in the Non-Finnish European population (allele frequency 9.1e-07)
Structural context available
Literature evidence available