S21S (p.Ser21Ser) variant of TMEM127 (Transmembrane protein 127)
S21S (p.Ser21Ser) in TMEM127 (Transmembrane protein 127) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
S21S (p.Ser21Ser) variant details
- p.Ser21Ser
- rs1573977946
- gnomAD 2-96265319-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.365
- AlphaMissense 0.43
- MetaLR 0.22
- MetaSVM -0.90
- CADD 15.00
- PolyPhen-2 0.13
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available