P27T (p.Pro27Thr) variant of TMEM127 (Transmembrane protein 127)
P27T (p.Pro27Thr) in TMEM127 (Transmembrane protein 127) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
P27T (p.Pro27Thr) variant details
- p.Pro27Thr
- gnomAD 2-96265303-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.549
- REVEL 0.42
- CADD 23.00
- PolyPhen-2 0.12
- SIFT 0.21
- Most common in the Latino/Admixed American population (allele frequency 2.7e-05)
- Structural context available
- Literature evidence available