P24P (p.Pro24Pro) variant of TMEM127 (Transmembrane protein 127)
P24P (p.Pro24Pro) in TMEM127 (Transmembrane protein 127) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
P24P (p.Pro24Pro) variant details
- p.Pro24Pro
- gnomAD 2-96265310-G-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.296
- AlphaMissense 0.27
- MetaLR 0.09
- MetaSVM -0.99
- CADD 15.40
- PolyPhen-2 0.03
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available
- Literature evidence available