L35M (p.Leu35Met) variant of TMEM127 (Transmembrane protein 127)
L35M (p.Leu35Met) in TMEM127 (Transmembrane protein 127) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
L35M (p.Leu35Met) variant details
- p.Leu35Met
- gnomAD 2-96265279-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.462
- REVEL 0.52
- CADD 23.00
- PolyPhen-2 0.94
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available