L31M (p.Leu31Met) variant of TMEM127 (Transmembrane protein 127)
L31M (p.Leu31Met) in TMEM127 (Transmembrane protein 127) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
L31M (p.Leu31Met) variant details
- p.Leu31Met
- gnomAD 2-96265291-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.529
- REVEL 0.50
- CADD 27.90
- PolyPhen-2 0.94
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available