L23L (p.Leu23Leu) variant of TMEM127 (Transmembrane protein 127)
L23L (p.Leu23Leu) in TMEM127 (Transmembrane protein 127) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
L23L (p.Leu23Leu) variant details
- p.Leu23Leu
- rs2104308188
- gnomAD 2-96265313-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.387
- AlphaMissense 0.09
- MetaLR 0.14
- MetaSVM -0.99
- CADD 14.90
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available