G8W (p.Gly8Trp) variant of TMEM127 (Transmembrane protein 127)
G8W (p.Gly8Trp) in TMEM127 (Transmembrane protein 127) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
G8W (p.Gly8Trp) variant details
- p.Gly8Trp
- gnomAD 2-96265360-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.577
- REVEL 0.46
- CADD 24.90
- PolyPhen-2 0.35
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available