G37G (p.Gly37Gly) variant of TMEM127 (Transmembrane protein 127)
G37G (p.Gly37Gly) in TMEM127 (Transmembrane protein 127) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
G37G (p.Gly37Gly) variant details
- p.Gly37Gly
- rs1573977865
- gnomAD 2-96265271-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.242
- AlphaMissense 0.13
- MetaLR 0.19
- MetaSVM -0.91
- CADD 13.80
- PolyPhen-2 0.89
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available