Y180H (p.Tyr180His) variant of TLR9 (Toll-like receptor 9)
Y180H (p.Tyr180His) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
Y180H (p.Tyr180His) variant details
- p.Tyr180His
- ExAC rs768844402
- gnomAD rs768844402
- Missense
- Variant Prioritization Score for Impact Estimate 0.42
- REVEL 0.26
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available