Y179N (p.Tyr179Asn) variant of TLR9 (Toll-like receptor 9)
Y179N (p.Tyr179Asn) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
Y179N (p.Tyr179Asn) variant details
- p.Tyr179Asn
- TOPMed rs1699591251
- gnomAD rs1699591251
- Missense
- Variant Prioritization Score for Impact Estimate 0.447
- REVEL 0.30
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available