V15M (p.Val15Met) variant of TLR9 (Toll-like receptor 9)
V15M (p.Val15Met) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
V15M (p.Val15Met) variant details
- p.Val15Met
- TOPMed rs1394861605
- gnomAD rs1394861605
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- REVEL 0.13
- CADD 22.90
- PolyPhen-2 0.82
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available