V122A (p.Val122Ala) variant of TLR9 (Toll-like receptor 9)
V122A (p.Val122Ala) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
V122A (p.Val122Ala) variant details
- p.Val122Ala
- ESP rs148085174
- ExAC rs148085174
- TOPMed rs148085174
- gnomAD rs148085174
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.15
- CADD 21.50
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available