T23A (p.Thr23Ala) variant of TLR9 (Toll-like receptor 9)
T23A (p.Thr23Ala) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
T23A (p.Thr23Ala) variant details
- p.Thr23Ala
- TOPMed rs1312227021
- gnomAD rs1312227021
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.09
- CADD 0.83
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available