T124N (p.Thr124Asn) variant of TLR9 (Toll-like receptor 9)
T124N (p.Thr124Asn) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
T124N (p.Thr124Asn) variant details
- p.Thr124Asn
- gnomAD rs974162456
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.05
- CADD 12.00
- PolyPhen-2 0.04
- SIFT 0.59
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available