T124A (p.Thr124Ala) variant of TLR9 (Toll-like receptor 9)
T124A (p.Thr124Ala) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
T124A (p.Thr124Ala) variant details
- p.Thr124Ala
- ExAC rs201783734
- gnomAD rs201783734
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.12
- CADD 14.70
- PolyPhen-2 0.01
- SIFT 0.20
- Most common in the South Asian population (allele frequency 2.4e-05)
- Structural context available