T113N (p.Thr113Asn) variant of TLR9 (Toll-like receptor 9)
T113N (p.Thr113Asn) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
T113N (p.Thr113Asn) variant details
- p.Thr113Asn
- gnomAD rs1699594197
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.03
- CADD 18.80
- PolyPhen-2 0.56
- SIFT 0.14
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available