S67R (p.Ser67Arg) variant of TLR9 (Toll-like receptor 9)
S67R (p.Ser67Arg) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
S67R (p.Ser67Arg) variant details
- p.Ser67Arg
- ExAC rs780558008
- gnomAD rs780558008
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.13
- CADD 18.90
- PolyPhen-2 0.03
- SIFT 0.03
- Most common in the East Asian population (allele frequency 7.7e-05)
- Structural context available