S149P (p.Ser149Pro) variant of TLR9 (Toll-like receptor 9)
S149P (p.Ser149Pro) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S149P (p.Ser149Pro) variant details
- p.Ser149Pro
- Ensembl rs1577981105
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.20
- CADD 8.45
- PolyPhen-2 0.00
- SIFT 0.07
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available