R90W (p.Arg90Trp) variant of TLR9 (Toll-like receptor 9)
R90W (p.Arg90Trp) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
R90W (p.Arg90Trp) variant details
- p.Arg90Trp
- gnomAD rs1441565360
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- REVEL 0.27
- CADD 23.90
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the East Asian population (allele frequency 5.1e-05)
- Structural context available