R90Q (p.Arg90Gln) variant of TLR9 (Toll-like receptor 9)
R90Q (p.Arg90Gln) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
R90Q (p.Arg90Gln) variant details
- p.Arg90Gln
- ExAC rs766103514
- TOPMed rs766103514
- gnomAD rs766103514
- Missense
- Variant Prioritization Score for Impact Estimate 0.18
- REVEL 0.12
- CADD 15.60
- PolyPhen-2 0.12
- SIFT 0.26
- Most common in the African/African-American population (allele frequency 6.1e-05)
- Structural context available