R62H (p.Arg62His) variant of TLR9 (Toll-like receptor 9)
R62H (p.Arg62His) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
R62H (p.Arg62His) variant details
- p.Arg62His
- TOPMed rs997645449
- gnomAD rs997645449
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- REVEL 0.04
- CADD 15.00
- PolyPhen-2 0.01
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available