R62C (p.Arg62Cys) variant of TLR9 (Toll-like receptor 9)
R62C (p.Arg62Cys) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
R62C (p.Arg62Cys) variant details
- p.Arg62Cys
- ExAC rs200596305
- TOPMed rs200596305
- gnomAD rs200596305
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.09
- CADD 18.00
- PolyPhen-2 0.02
- SIFT 0.11
- Most common in the South Asian population (allele frequency 3.7e-05)
- Structural context available