R170S (p.Arg170Ser) variant of TLR9 (Toll-like receptor 9)
R170S (p.Arg170Ser) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R170S (p.Arg170Ser) variant details
- p.Arg170Ser
- TOPMed rs1011356526
- gnomAD rs1011356526
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- REVEL 0.21
- CADD 16.40
- PolyPhen-2 0.02
- SIFT 0.15
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available