R170H (p.Arg170His) variant of TLR9 (Toll-like receptor 9)
R170H (p.Arg170His) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
R170H (p.Arg170His) variant details
- p.Arg170His
- ExAC rs199767102
- TOPMed rs199767102
- gnomAD rs199767102
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.13
- CADD 21.90
- PolyPhen-2 0.81
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 7e-05)
- Structural context available