P61S (p.Pro61Ser) variant of TLR9 (Toll-like receptor 9)
P61S (p.Pro61Ser) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
P61S (p.Pro61Ser) variant details
- p.Pro61Ser
- ExAC rs770637836
- TOPMed rs770637836
- gnomAD rs770637836
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.09
- CADD 13.80
- PolyPhen-2 0.22
- SIFT 0.10
- Most common in the Latino/Admixed American population (allele frequency 7e-05)
- Structural context available