P54H (p.Pro54His) variant of TLR9 (Toll-like receptor 9)
P54H (p.Pro54His) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
P54H (p.Pro54His) variant details
- p.Pro54His
- gnomAD rs1257387558
- Missense
- Variant Prioritization Score for Impact Estimate 0.605
- REVEL 0.48
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available