P39A (p.Pro39Ala) variant of TLR9 (Toll-like receptor 9)
P39A (p.Pro39Ala) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
P39A (p.Pro39Ala) variant details
- p.Pro39Ala
- ExAC rs750628960
- gnomAD rs750628960
- Missense
- Variant Prioritization Score for Impact Estimate 0.0576
- REVEL 0.05
- CADD 0.95
- PolyPhen-2 0.00
- SIFT 0.51
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available