P183T (p.Pro183Thr) variant of TLR9 (Toll-like receptor 9)
P183T (p.Pro183Thr) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
P183T (p.Pro183Thr) variant details
- p.Pro183Thr
- TOPMed rs777760744
- gnomAD rs777760744
- Missense
- Variant Prioritization Score for Impact Estimate 0.547
- REVEL 0.45
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available