P123S (p.Pro123Ser) variant of TLR9 (Toll-like receptor 9)
P123S (p.Pro123Ser) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P123S (p.Pro123Ser) variant details
- p.Pro123Ser
- ExAC rs56287816
- TOPMed rs56287816
- gnomAD rs56287816
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.06
- CADD 15.20
- PolyPhen-2 0.08
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 9.1e-05)
- Structural context available