P116S (p.Pro116Ser) variant of TLR9 (Toll-like receptor 9)
P116S (p.Pro116Ser) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
P116S (p.Pro116Ser) variant details
- p.Pro116Ser
- TOPMed rs1026141784
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.03
- CADD 19.10
- PolyPhen-2 0.08
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available