P10L (p.Pro10Leu) variant of TLR9 (Toll-like receptor 9)
P10L (p.Pro10Leu) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
P10L (p.Pro10Leu) variant details
- p.Pro10Leu
- ESP rs370157255
- ExAC rs370157255
- TOPMed rs370157255
- gnomAD rs370157255
- Missense
- Variant Prioritization Score for Impact Estimate 0.442
- REVEL 0.34
- CADD 22.00
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available