P109R (p.Pro109Arg) variant of TLR9 (Toll-like receptor 9)
P109R (p.Pro109Arg) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P109R (p.Pro109Arg) variant details
- p.Pro109Arg
- gnomAD rs1295652148
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.09
- CADD 23.00
- PolyPhen-2 0.41
- SIFT 0.05
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available