P100L (p.Pro100Leu) variant of TLR9 (Toll-like receptor 9)
P100L (p.Pro100Leu) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
P100L (p.Pro100Leu) variant details
- p.Pro100Leu
- ExAC rs781694864
- TOPMed rs781694864
- gnomAD rs781694864
- Missense
- Variant Prioritization Score for Impact Estimate 0.506
- REVEL 0.31
- CADD 24.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available