N182K (p.Asn182Lys) variant of TLR9 (Toll-like receptor 9)
N182K (p.Asn182Lys) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
N182K (p.Asn182Lys) variant details
- p.Asn182Lys
- ExAC rs749405730
- gnomAD rs749405730
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.20
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available