N129K (p.Asn129Lys) variant of TLR9 (Toll-like receptor 9)
N129K (p.Asn129Lys) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
N129K (p.Asn129Lys) variant details
- p.Asn129Lys
- TOPMed rs1262811850
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.11
- CADD 23.50
- PolyPhen-2 0.91
- SIFT 0.02
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available