L94F (p.Leu94Phe) variant of TLR9 (Toll-like receptor 9)
L94F (p.Leu94Phe) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
L94F (p.Leu94Phe) variant details
- p.Leu94Phe
- gnomAD rs1699594948
- Missense
- Variant Prioritization Score for Impact Estimate 0.65
- REVEL 0.56
- CADD 24.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available