L26P (p.Leu26Pro) variant of TLR9 (Toll-like receptor 9)
L26P (p.Leu26Pro) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
L26P (p.Leu26Pro) variant details
- p.Leu26Pro
- ExAC rs754311214
- gnomAD rs754311214
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.13
- CADD 18.10
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available