L150V (p.Leu150Val) variant of TLR9 (Toll-like receptor 9)
L150V (p.Leu150Val) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L150V (p.Leu150Val) variant details
- p.Leu150Val
- TOPMed rs919277696
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.18
- CADD 22.10
- PolyPhen-2 0.38
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available