L11M (p.Leu11Met) variant of TLR9 (Toll-like receptor 9)
L11M (p.Leu11Met) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
L11M (p.Leu11Met) variant details
- p.Leu11Met
- gnomAD rs1270141629
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.23
- CADD 19.40
- PolyPhen-2 0.89
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available