I114V (p.Ile114Val) variant of TLR9 (Toll-like receptor 9)
I114V (p.Ile114Val) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
I114V (p.Ile114Val) variant details
- p.Ile114Val
- gnomAD rs1157043280
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.14
- CADD 22.00
- PolyPhen-2 0.98
- SIFT 0.07
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available