H85P (p.His85Pro) variant of TLR9 (Toll-like receptor 9)
H85P (p.His85Pro) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
H85P (p.His85Pro) variant details
- p.His85Pro
- gnomAD rs1299201604
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.17
- CADD 16.90
- PolyPhen-2 0.70
- SIFT 0.29
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available