H79Q (p.His79Gln) variant of TLR9 (Toll-like receptor 9)
H79Q (p.His79Gln) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
H79Q (p.His79Gln) variant details
- p.His79Gln
- rs5743843
- UniProt VAR 052364
- ExAC rs5743843
- TOPMed rs5743843
- Missense
- Variant Prioritization Score for Impact Estimate 0.0476
- REVEL 0.03
- CADD 2.43
- PolyPhen-2 0.08
- SIFT 0.27
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available