H77Q (p.His77Gln) variant of TLR9 (Toll-like receptor 9)
H77Q (p.His77Gln) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
H77Q (p.His77Gln) variant details
- p.His77Gln
- gnomAD rs1319660926
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.16
- CADD 22.60
- PolyPhen-2 0.97
- SIFT 0.34
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available