H40Y (p.His40Tyr) variant of TLR9 (Toll-like receptor 9)
H40Y (p.His40Tyr) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
H40Y (p.His40Tyr) variant details
- p.His40Tyr
- gnomAD rs1229630759
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.06
- CADD 3.86
- PolyPhen-2 0.05
- SIFT 0.97
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available