H111Q (p.His111Gln) variant of TLR9 (Toll-like receptor 9)
H111Q (p.His111Gln) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
H111Q (p.His111Gln) variant details
- p.His111Gln
- ExAC rs747260036
- gnomAD rs747260036
- Missense
- Variant Prioritization Score for Impact Estimate 0.18
- REVEL 0.05
- CADD 16.20
- PolyPhen-2 0.31
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available