G63D (p.Gly63Asp) variant of TLR9 (Toll-like receptor 9)
G63D (p.Gly63Asp) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
G63D (p.Gly63Asp) variant details
- p.Gly63Asp
- ExAC rs772719609
- gnomAD rs772719609
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.16
- CADD 0.28
- PolyPhen-2 0.03
- SIFT 0.25
- Most common in the Latino/Admixed American population (allele frequency 2.4e-05)
- Structural context available