G41S (p.Gly41Ser) variant of TLR9 (Toll-like receptor 9)
G41S (p.Gly41Ser) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
G41S (p.Gly41Ser) variant details
- p.Gly41Ser
- ExAC rs200055519
- TOPMed rs200055519
- gnomAD rs200055519
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.19
- CADD 7.63
- PolyPhen-2 0.17
- SIFT 0.42
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available