G27D (p.Gly27Asp) variant of TLR9 (Toll-like receptor 9)
G27D (p.Gly27Asp) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G27D (p.Gly27Asp) variant details
- p.Gly27Asp
- gnomAD rs1356994585
- Missense
- Variant Prioritization Score for Impact Estimate 0.465
- REVEL 0.37
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available