G176S (p.Gly176Ser) variant of TLR9 (Toll-like receptor 9)
G176S (p.Gly176Ser) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
G176S (p.Gly176Ser) variant details
- p.Gly176Ser
- Ensembl rs1479202525
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.19
- CADD 23.70
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available